Bladder cancer
INACTIVE --- It’s getting personalised: first-line therapy of synchronous or metachronous mUCaBrody (59 years old)
Brody is a 59-year-old zookeeper who enjoys working in a calm environment. Not surprisingly, his favourite animals are the sloths. At least they don’t disturb him during his work because they are asleep most of the time.
He was diagnosed with MIBC T2N0M0, for which he underwent neoadjuvant dd-MVAC followed by radical cystectomy. He presents 3 months after completing neoadjuvant chemotherapy.
Assessment summary:
- ECOG PS: 0
- Haemoglobin: 12.5 g/dl
- No peripheral neuropathy
- No hearing impairment
- GFR: 86 ml/min
- CT scan reveals multiple lung metastases, biopsy compatible with UCa
- PD-L1 expression: low
- Activating FGFR3 mutation in diagnostic biopsy specimen