Renal Cell Carcinoma
Local therapy for mRCC

Toni (64 years old)

Toni, a 64-year-old non-binary person, has had enough of cold, rainy weather. Their life-long dream was to pack up and move to a more southern place, where the sun always shines and temperatures don’t fall below 20°C. Before setting off on their journey, they went for a check-up with a general physician because of fatigue.

Assessment summary:

  • ECOG PS: 0
  • KPS: 90%
  • CT scan:
    • Large renal tumour on the left side
    • 3 liver and 2 bone lesions suspicious for metastases (confirmed by liver biopsy)
  • Blood work: elevated erythrocyte sedimentation rate, otherwise normal

Which of the following treatment options would you choose for this patient?