Breast cancer
INACTIVE --- Brain metastases in patients with HER2+ breast cancerTelma (60 years old)
Telma is a 60-year-old pianist. She presents with headache and nausea, which she experiences since the last 2 months.
- Medical history: diagnosed with early breast cancer almost 2 years ago
- ER 0%, PgR 0%, HER2 3+
- Received adjuvant anthracycline/taxane and trastuzumab + pertuzumab (completed 6 months ago)
- No relevant comorbidities
- Brain CT: limited number of suspicious spots
- Neurological clinical exam: normal
- PET scan: single liver lesion and pleural effusion
- Brain MRI: 3 brain lesions
- Tumour biology (biopsy liver lesion): confirmation of metastasis of breast origin, invasive ductal carcinoma, ER 0%, PgR 0%, HER2 3+
- ECOG PS: 0