Brunhilde (89 years old)

Brunhilde is 89 years old and lives in rural Bavaria, a 2-hour car ride away from the next city. Unfortunately, she fell during a walk in the woods and hurt her leg badly. She was transferred to the local hospital, where an X-ray revealed a fracture of the right femur due to a suspicious lesion.

Assessment summary:

• Postmenopausal
• Medical history:
  • Diabetes mellitus type 2
  • Ulcerative colitis
  • Long QT syndrome
  • ECOG PS: 2
• No family history of breast cancer 
• Biopsy of the bone lesion: breast cancer, ER 100%, PgR 100%, HER2 IHC 0, G1
• Imaging:
  • 2.5 cm tumour in the right breast, 1 suspicious axillary lymph node
  • 1 lesion suspicious for metastasis in right femur, no further metastases
• Germline BRCA-status: wild type
• PIK3CA-status in the tumour: wild type