Bladder cancer
Management of M0 muscle-invasive bladder cancer beyond radical cystectomy

Lena (69 years old)

Lena, a 69-year-old woman who loves to knit sweaters for her 5 grandchildren, underwent a TURBT that indicated MIBC.

 

Assessment summary:

  • Ultrasound: no hydronephrosis

  • Imaging: suggestive for cT3b N0M0 disease

  • No concomitant CIS

  • Normal renal function

  • No peripheral neuropathy

  • ECOG PS: 1

  • No baseline hearing loss

The patient refuses to undergo RC.

What is the most appropriate treatment choice for this patient?