Olivia (72 years old)

Olivia, 72 years old, has collected stamps since her childhood. After travelling to so many countries, now her collection is quite valuable.

She was diagnosed with UCa of bladder with lung metastases, for which she received 6 cycles of gemcitabine + cisplatin. At the end of chemotherapy, CT revealed new lung lesions; pembrolizumab was started. 9 months later, she shows again progressive disease.

Assessment summary:

• No relevant medical history
• ECOG PS: 2; increasing breathlessness and cough
• CT chest, abdomen and pelvis: enlarged lesions in lungs
• FGFR2/3 status in tumour tissue specimen: activating FGFR3 gene fusion

The patient started erdafitinib with partial response, but 2 months later, she develops blurred vision making her unable to drive. On ophthalmologic examination, a diagnosis of grade 2 central serous chorioretinopathy was made. She is being followed up by an ophthalmologist with regular examinations.