Breast cancer
INACTIVE --- Systemic therapy for early stage triple-negative breast cancer

Betty (69 years old)

Betty is a 69-year-old active woman who used to work at a shelter for birds and wildlife. She still volunteers at busy times. Recently, she was diagnosed with breast cancer on the left side.

Assessment summary

  • Postmenopausal
  • No family history of breast or ovarian cancer
  • Medical history: heart failure with reduced LVEF (NYHA class II) – treatment with ACE inhibitor, ECOG PS: 0
  • Tumour size: cT1c (16 mm), LN status: cN1
  • Tumour biology:
    • Ductal invasive carcinoma of NST
    • ER 0%, PgR 0%, HER2 0
    • Ki67 85%
    • G3
  • CT scan thorax/abdomen and bone scan: no metastases

Which neoadjuvant chemotherapy regimen would you choose for this patient?