Bladder cancer
Follow-up surveillance regimes to consider for (very) high-risk NMIBC and MIBC

Bruce (63 years old)

Bruce, 63 years old, is the coach of the women’s lacrosse team in his village. This year, they haven't won a game yet.

He presented with macroscopic haematuria, which led to the discovery of a high-risk NMIBC. After the first cycle of 6 instillations of BCG, he relapsed.

Assessment summary:

  • Former smoker (50 years)
  • Medical history: gastroesophageal reflux
  • Family history: sister with thyroid cancer
  • Creatinine level: 91 µmol/l, eGFR: 78 ml/min
  • Pathological report TURBT:
    • High-grade papillary UCa
    • Muscle in specimen, free of tumour
    • pT1b without CIS
    • No FGFR alteration
  • CT scan of thorax/abdomen/pelvis: no distant lesions or synchronous UTUC
  • Robot-assisted laparoscopic cystectomy + PLND:
    • Urinary diversion by ileal conduct
    • Pathology report: pT2 + CIS on prostatic urethra N0 (0/37) R0

Surveillance with routine imaging with CT of the thorax and abdomen is planned for this patient. Vitamin B12 levels will be measured annually.

Which option would you choose as an additional surveillance strategy for this patient?