Bladder cancer
Follow-up surveillance regimes to consider for (very) high-risk NMIBC and MIBC

Henri (63 years old)

Henri is a 63-year-old consultant who enjoys glamping. The glamp sites he picks for his trips are usually located in the middle of nowhere, as he is not a people person…

He presented with macroscopic haematuria, which led to the discovery of a high-risk NMIBC. After the first cycle of 6 instillations of BCG, he relapsed.

Assessment summary:

  • Former smoker (50 years)
  • Medical history: gastroesophageal reflux
  • Family history: sister with thyroid cancer
  • Creatinine level: 91 µmol/l, eGFR: 78 ml/min
  • Pathological report TURBT:
    • HG papillary UCa
    • Muscle in specimen, free of tumour
    • pT1b without CIS
    • No FGFR alteration
  • CT scan of thorax/abdomen/pelvis: no distant lesions or synchronous UTUC
  • Robot-assisted laparoscopic cystectomy + pelvic lymph node dissection (PLND):
    • Urinary diversion by orthotopic neobladder
    • Pathology report: pT0 N0 (0/37) R0

Surveillance with routine imaging with CT of the thorax and abdomen is planned for this patient. Vitamin B12 levels will be measured annually.

Which option would you choose as an additional surveillance strategy for this patient?