Case 1: Daniela (69 years old)

Daniela, 69 years old, has always been an early riser, she starts her day with a quiet walk through her garden before the city wakes up.

She recently underwent cystoscopy for painless haematuria, revealing a papillary bladder tumour. Her past medical history includes stable coronary artery disease, hypertension and borderline diabetes. She quit smoking 25 years ago.

Assessment summary:

• Diagnostic transurethral resection of bladder tumour (TURBT), pathological review:
  • At least pT2 urothelial carcinoma (UCa)
  • Unifocal, no concomitant carcinoma in situ (CIS)
• Imaging: suggestive for cT3N0cM0
• Ultrasound: no hydronephrosis
• eGFR: 66 ml/min
• No peripheral neuropathy
• No hearing impairment
• ECOG PS: 0
• Cardiac ejection fraction: 55%

Multidisciplinary tumour board assessed that patient is a candidate for radical cystectomy (RC) + pelvic lymph node dissection (PLND).