Bladder cancer
Molecular diagnostics in the era of targeted therapies for mUCaCase 1: Ahmad (67 years old)
Ahmad, 67 years old, dedicates his time to environmental conservation efforts, planting trees and cleaning up local parks to preserve nature for future generations. He was diagnosed 1 year ago with primary mUCa of the bladder with retroperitoneal and intrathoracic lymph node metastases.
He received 6 cycles of gemcitabine + carboplatin followed by maintenance avelumab. However, the last CT scan revealed new lung metastases. A biopsy confirmed progressing mUCa.
Assessment summary:
- Medical history: controlled diabetes mellitus
- ECOG PS: 1
- GFR: 45 ml/min
- No peripheral neuropathy
- No hearing impairment