Breast cancer
Adjuvant systemic treatment of luminal A/B early breast cancerSandra (59 years old)
Sandra, 59 years old, is a veterinarian specialised in farm animals. She has 3 dogs that she often walks with along the sea shore, nearby her home. The results of her screening mammogram were abnormal.
Assessment summary
- No relevant medical history or family history of cancer
- Postmenopausal
- Stage and tumour biology (core biopsy) at diagnosis:
- cT2N0M0
- G2, invasive carcinoma of no special type, ER 100%, PgR 90%, HER2 negative (IHC 0), Ki67 30%
- Breast conserving surgery with oncoplastic techniques + SLNB
- Pathology report:
- G2 bifocal invasive carcinoma, 27 mm in largest foci, pT2
- Intermediate grade DCIS in 15%
- Lymphovascular invasion present, no perineural invasion
- R0 resection
- pN0 (0/4 sn)
- Multidisciplinary board meeting:
- Gene expression profiling (21-gene assay): recurrence score result of 21
- Postoperative RT and systemic therapy