Bladder cancer
Follow-up surveillance regimes to consider for (very) high-risk NMIBC and MIBC

Gabriel (74 years old)

Gabriel is a 74-year-old retired military soldier. Now he plays funny rescue missions with his grandchildren when he has to babysit them.

He underwent cystoscopy for painless haematuria, which revealed a 4 cm papillary tumour.

Assessment summary:

  • No relevant medical history or family history
  • Complete TURBT, pathological review: minimal pT2 UCa
  • Imaging: suggestive of cT2 cN0 cM0
  • CT scan of thorax/abdomen/pelvis: no distant lesions or synchronous UTUC
  • Trimodality therapy (TMT):
    • No residual tumour on second TURBT
    • Intensity modulated radiotherapy (RT) on the entire bladder (55 Gy in 20 fractions)
    • Chemotherapy with fluorouracil and mitomycin C

Re-TURBT of the resection site and random bladder biopsies did not show any residual tumour.

It is now 3 months after completion of RT.

Which of the following surveillance options would you choose for this patient?