Teresa (59 years old)

Teresa, 59 years old, runs a travel agency and convinces a lot of her clients about the beauty of Asia. She was earlier diagnosed with early breast cancer.

• No relevant comorbidities
• 4 years ago: diagnosed with early breast cancer
  • ER 0%, PgR 0%, HER2 IHC 3+
  • Received adjuvant anthracycline/taxane and trastuzumab
• 1 year ago: diagnosis metastatic breast cancer (bone, lymph nodes, brain)
  • Symptomatic: bone pain, headache, nausea
  • Local treatment brain metastases: WBRT
  • Systemic treatment: taxane + trastuzumab + pertuzumab
  • Good response in brain, partial response of extracranial disease
• Now, progressive disease:
  • Progression of some of the bone lesions and new liver lesion
  • Progression in 1 existing brain lesion and 1 new brain lesion
  • Asymptomatic
  • ECOG PS: 1