Prostate cancer
ESMO 2025Man, 67 years old
Man, 67 years old, has an active career working as a lawyer. He's a dedicated grandparent to 2 young grandchildren (2 and 4 years old), and he enjoys cycling and plays in an orchestra.
Unfortunately, he is recently diagnosed with de novo mHSPC.
- Medical history: type 2 diabetes mellitus, under control with atorvastatin and metformin
- ECOG PS: 0
- PSA: 13 ng/ml
- Lab values: normal
- Prostate biopsy: ISUP grade group 4 (Gleason score 4+4)
- Bone scan: 11 bone metastases (4 on the spine, 3 in the pelvis, 3 in the left ribs, 1 in left femur), no visceral metastases
- CT scan: locally advanced prostatic mass, few positive pelvic LNs, no visceral metastases
- No targetable germline or somatic mutations detected
- The patient is chemotherapy-fit and will receive triplet therapy