Nadine (60 years old)

Nadine, 60 years old, owns a pottery and creates special flower vases. She experiences headache with nausea during the last 2 months which led to a brain CT during the assessment. She was diagnosed with metastatic breast cancer.

• No relevant medical history
• Brain CT: multiple suspicious spots
• Neurological clinical exam: normal
• PET scan: breast lesion, multiple liver lesions and pleural effusion
• Brain MRI: 12 brain lesions (all <1 cm, location: sub- and infratentorial)
• Tumour biology (biopsy breast lesion): ER 0%, PgR 0%, HER2 IHC 3+
• ECOG PS: 0