Bladder cancer
INACTIVE --- It’s getting personalised: first-line therapy of synchronous or metachronous mUCaViolet (72 years old)
Violet, 72 years old, was once a famous ballerina. Now she spends her time re-watching videos where she's dancing. She misses the good old days.
She was diagnosed with MIBC T2N1M0 and underwent neoadjuvant dd-MVAC followed by radical cystectomy. The pathological stage after chemotherapy was ypT2N0. Chemotherapy was well tolerated, with grade 1 neutropenia and grade 1 anaemia. 15 months after surgery, she presents with lung metastasis.
Assessment summary:
- ECOG PS: 0
- Biopsy compatible with UCa
- Peripheral neuropathy grade I
- No hearing impairment
- GFR: 45 ml/min
- PD-L1 expression in tumour sample from cystectomy specimen: negative