Julia (67 years old)

Julia, a 67-year-old woman, fell on her back during window cleaning. An X-ray showed a suspicious lesion in the spine. A further diagnostic workup was performed, which revealed metastatic breast cancer.

Assessment summary:

• Postmenopausal
• No relevant medical history, ECOG PS: 0
• No family history of breast cancer
• Imaging:
  • 4 cm tumour in the left breast, 3 suspicious axillary lymph nodes
  • Multiple suspicious lesions in the spine
  • 2 lesions suspicious for metastases in the liver
• Biopsy of bone metastasis: breast cancer, NST, ER 90%, PgR 60%, HER2 IHC 1+, G2
• Haematology and biochemistry: all values normal
• Germline BRCA-status: wild type
• PIK3CA-status in the tumour: wild type