Prostate cancer
Tailoring treatment for metastatic hormone-sensitive prostate cancer

Case 7: Antonio

Antonio, 67 years old, was recently diagnosed with mHSPC.

Assessment summary:

  • Medical history: no abnormalities
  • ECOG PS: 0
  • PSA: 41 ng/ml
  • Prostate biopsy: ISUP grade group 4 (Gleason score 4+4)
  • Bone scan: 3 metastases (on vertebral bodies)
  • CT: locally advanced prostatic mass; no lymph node or visceral metastatic disease

Antonio went to a different hospital to get a second opinion.

  • PSMA-PET/CT: 9 metastases (6 on vertebral bodies, 1 in left ischium and 2 on the left rib), few positive pelvic LNs
  • He will start treatment with ADT

Which of the following options would you choose for this patient?