Bladder cancer
Management of BCG-pretreated (very) high-risk NMIBCMireille (77 years old)
Mireille, a 77-year-old former librarian who enjoys bookbinding, is suspected of having bladder cancer.
Assessment summary:
- No relevant medical history
- ECOG PS: 0
- Cystoscopy: papillary tumour of 4.5 cm at the right bladder wall
- Urine cytology: negative for HG UCa (according to the Paris system)
- Conventional TURBT: resection visually complete, pathological review:
- pT1 HG
- Pure UCa
- No LVI
- Muscle in specimen
- Second TURBT: no residual disease
- CT urography: cN0, no concomitant upper tract tumour
BCG induction was started and followed by maintenance BCG. 9 months after start of BCG therapy (i.e. BCG induction and 2 courses of BCG maintenance completed), the patient presents with a papillary tumour of 1 cm near the previous resection side. Conventional TURBT confirms pTa HG (muscle in specimen, no LVI).