Amanda (40 years old)

Amanda is a 40-year-old safety coordinator in a company that processes garbage. She’s not afraid of getting her hands dirty herself and supports her team in every way possible. While showering after a long working day, she noted a lump in her right breast.

Assessment summary

• Premenopausal
• No family history of breast or ovarian cancer
• No relevant medical history, ECOG PS: 0
• Tumour size: cT2 (25mm), LN status: cN1
• Tumour biology:
  • Ductal invasive carcinoma of NST
  • ER 0%, PgR 0%, HER2 IHC 0
  • Ki67 75%
  • G3
• CT scan thorax/abdomen and bone scan: no metastases
• Genetic testing: no BRCA mutation
• Primary systemic therapy started with EC dose dense
  • After 4 cycles, disease progression was detected