Bladder cancer
INACTIVE --- It’s getting personalised: first-line therapy of synchronous or metachronous mUCaChristine (54 years old)
Christine is a 54-year-old librarian passionate about fantasy novels. She is a huge fan of the Game of Thrones series and every time she gets cold chills, she says: “Winter is coming.”
She was diagnosed with metastatic UCa of the bladder during investigation of dysuria. Somatic tumour testing did not show FGFR2 or FGFR3 alterations.
Assessment summary:
- No relevant past medical history
- CT scan of chest, abdomen and pelvis: diffuse liver and lung metastases
- ECOG PS: 1
- GFR: 90 ml/min
- PD-L1 expression: high
She received 4 cycles of gemcitabine + cisplatin with partial response. She has now developed significant neuropathy and fatigue and does not want more of this chemotherapy.