Breast cancer
UPDATED --- Radiotherapy for early breast cancer

Grace (34 years old)

Grace is a 34-year-old pastry chef who owns her own pastry shop. She makes the most delicious macarons. It’s smart to order her macarons in advance because they are always sold out immediately after opening in the morning. She was diagnosed with right-sided breast cancer.

Assessment summary

  • Premenopausal
  • No relevant medical history
  • Family history of breast cancer
  • ECOG PS: 0
  • Tumour size: cT1c, lymph node status: cN0
  • Tumour biology: ER 0%, PgR 0%, HER2 IHC 0, Ki67 29%, G2, basal-like
  • CT scan chest/abdomen and bone scan: cM0
  • BRCA germline mutation
  • Primary bilateral mastectomy + SLNB:
    • pT1cN0
    • LVI absent
    • R0 resection

Which option would you choose for this patient?