Breast cancer
UPDATED --- Radiotherapy for early breast cancer

Seiko (36 years old)

Seiko, 36 years old, is a bioinformatician working with whole genome sequencing data. She is fascinated by the human genome and tries to unravel the yet unsolved mysteries of our DNA. Unfortunately, she was diagnosed with left-sided breast cancer.

Assessment summary

  • Premenopausal
  • No relevant medical history
  • No family history of breast or ovarian cancer
  • Tumour size: cT2, lymph node status: cN0
  • Tumour biology: ER 0%, PgR 0%, HER2 IHC 0, Ki67 22%, G3, basal-like
  • CT chest/abdomen and bone scan: cM0
  • No BRCA germline mutation
  • Received primary systemic therapy: 4x ddEC - 12x T
  • Lumpectomy + SLNB
    • ypT1cN0
    • R0 resection
    • LVI present

Which option would you choose for this patient?