Bladder cancer
Histological subtypes of (N)MIBC: managed differently compared to pure UCa?

Damon (33 years old)

Damon, 33 years old, enjoys listening to classical music more than anything else. Even during dinner, music is playing.

He is worried about recurrent haematuria and decides to pay his doctor a visit.

Assessment summary:

  • Comorbidities:
    • Spina bifida
    • Indwelling catheter
  • No paralysis
  • Tumour at right bladder wall
  • Maximal TURBT:
    • Minimal pT2 UCa + squamous differentiation
    • LVI
    • Unifocal, no concomitant CIS
  • Imaging: suggestive of cT3bN0M0
  • Normal renal function, cisplatin eligible
  • ECOG PS: 1

   

Which treatment option would you choose for this patient?