Renal Cell Carcinoma
Systemic therapy for mRCC: second line and beyondElena (64 years old)
Elena is a 64-year-old Slavic history and culture lover. In her free time, she studies Slavic languages too. She was diagnosed with primary bone metastatic ccRCC on the left side 9 months ago.
Assessment summary:
- Histology confirmed with biopsy
- At least cT3aN0M1 with infiltration of left renal vein
- IMDC: poor risk
- Medical history: pulmonary embolism, tricuspid insufficiency grade I, LVEF is normal
She started first-line therapy with nivolumab + ipilimumab.
- After 2 months: 1 bone lesion increased in size
- Asymptomatic