A 67-year-old man diagnosed with non-metastatic PCa and high-risk features

A 67-year-old man was recently diagnosed with prostate cancer.

Medical history: no relevant comorbidities or medication
ECOG PS: 0
PSA: 28.6 ng/ml
Other lab values: normal
Clinical stage: cT3a
mpMRI: PI-RADS 5 lesion in the left peripheral zone with evidence of extracapsular extension; no seminal vesicle invasion
Prostate biopsy: ISUP grade group 5 (Gleason score 4+5)
Bone scan and CT scan:
- No pelvic lymph node involvement
- No distant metastases