Lower Urinary Tract Dysfunction
Management of non-neurogenic female OAB

Mary (61 years)

Mary, 61 years old, loves to host bingo nights at the local community centre. Since 5 months, she needs to wake up at night to void 2-3 times. It has a significant impact on the quality of her sleep and the quality of her life. During the day, she occasionally loses urine with urgency before reaching the toilet. Bladder training and advice on fluid management did not help.


Medical history: Hypertension.
Clinical examination: Gynaecological: normal. No stress urinary incontinence. Weight: 60 kg. Blood pressure: 180/100 mmHg, heart pulse: 80 bpm. Cardiac and pulmonary investigation: normal.
Urinalysis: Normal.
Bladder scan: No post void residual.
Bladder diary: Frequency: day 7x, night 3x. Voided volumes: 30-250 ml. 24h diuresis: 1450 ml (12% during the night). Urine leakage: 2x, small amount.

What is the most appropriate treatment choice for this patient?