Renal cell carcinoma
INACTIVE --- First-line systemic therapy in mRCCRobert (82 years old)
Robert, 82 years old, was diagnosed with pancreatic metastases from clear-cell RCC (ccRCC) which occurred 12 years from nephrectomy.
Assessment summary:
- Medical history
- Hypertension controlled by antihypertensive drugs
- Aortic stent placement 7 years ago
- Left radical nephrectomy 12 years ago (ccRCC of 3.1 cm, ISUP grade 2, surgical staging pT1 N0)
- ECOG PS: 0
- KPS: 90%
- CT scan: progressive hypervascular lesions of the pancreas (biopsy-proven metastases of ccRCC)
- Blood work:
- Haemoglobin: 11.8 g/dl (12-13 g/dl)
- Neutrophils: 7.2x109/l (2.0-7.0x109/l )
- Platelets: 455x109/l (150-400x109/l)
- Calcium: 10.1 mg/dl (8.5-10.2 mg/dl)
- LDH: 350 U/l (135-225 U/l)
- Geriatric screening: patient considered candidate for oncologic treatment, with controlled comorbidities and a Geriatric 8 (G8) screening tool score of 15/17*
*healthy patients with a G8 score >14 should receive the same treatment as younger patients according to SIOG guidelines