Breast cancer

Progression after CDK4/6i + ET for HR+ HER2- MBC. What now?

Last updated: 20.02.2025

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Case 1 - Second line
Case 2 - Second line, rapid progression
Case 3 - Second line, imminent organ failure
Case 4 - Second line, somatic ESR1 mutation
Case 5 - Second line, somatic PIK3CA mutation
Case 6 - Second line, somatic ESR1 and PIK3CA mutations
Case 7 - Second line, germline BRCA1 mutation
Case 8 - Third line, HER2-low

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