Renal Cell Carcinoma

Local therapy for mRCC

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Educational Objective: Identify patients with metastatic ccRCC who will benefit the most from immediate, deferred or no cytoreductive nephrectomy (CN) and metastasis-directed therapy.
Specialty: Urology, Medical oncology, Clinical oncology
Target Audience: Specialists (CME: basic, intermediate), Residents (senior)
Latest update: May 2024

The role of CN and metastasis-directed therapy (including surgery, ablative therapies and radiotherapy) in the treatment of mRCC is evolving. However, the precise role of CN and its timing in relation to systemic therapy remains controversial.