Prostate cancer
Personalising care for patients with biochemical recurrence

Case 1: Manuel

Manuel, 74 years old.

Consider this patient’s medical history:

  • 5 years ago: radical prostatectomy for T2N0M0 PCa (ISUP grade group 3 (Gleason 4+3))
  • 2 years ago: early prostate bed salvage RT without ADT for BCR (PSA: 0.22 ng/ml)

Follow-up information today:

  • PSA: 1.2 ng/ml
  • PSA-DT: 7 months
  • Asymptomatic, no relevant comorbidities
  • ECOG PS: 1
  • PSMA-PET/CT: uptake in right acetabulum and L1 spinous process with no morphologic lesion on the CT

Which of the following treatment options would you choose for this patient?