Breast cancer
Adjuvant systemic treatment of luminal A/B early breast cancer in postmenopausal womenCora (59 years old)
Cora, 59 years old, is a veterinarian specialised in farm animals. She has 3 dogs that she often walks with along the seashore, nearby her home. The results of her screening mammogram were abnormal.
Assessment summary
- No relevant medical history
- No family history of cancer
- Postmenopausal
- Stage and tumour biology (core biopsy) at diagnosis:
- cT2N0M0
- G2, invasive carcinoma of NST, ER 100%, PgR 90%, HER2 IHC 0, Ki67 30%
- BCS with oncoplastic techniques + SLNB
- Pathology report:
- G2 bifocal invasive carcinoma, 27 mm in largest foci, pT2
- Intermediate grade DCIS in 15%
- LVI present, no perineural invasion
- R0 resection (free margins)
- pN0 (0/4 sn)
- Multidisciplinary board meeting:
- Gene expression profiling: low risk
- Postoperative RT and systemic therapy + bisphosphonates