Bladder cancer
New hope for patients progressing after prior treatment for mUCaAnnalisa (71 years old)
Every Sunday, 71-year-old Annalisa prepares an elaborate miniature meal for her hamster Cupcake, turning his Sunday’s dining experiences into tiny culinary adventures…
Unfortunately, Annalisa underwent cystectomy for pT2N0M0 UCa of the bladder. 3 years later, retroperitoneal lymph node metastases were discovered and gemcitabine + cisplatin treatment was started, followed by avelumab maintenance therapy. Now, 14 months after completing gemcitabine + cisplatin, avelumab maintenance is still ongoing but she presents with new metastases.
Assessment summary:
- Former smoker (50 pack years)
- Medical history: moderate chronic obstructive pulmonary disease
- ECOG PS: 1
- CT scan reveals new and enlarged lesions in the retroperitoneal lymph nodes and new bone lesions
- GFR: 60 ml/min
- FGFR2/3 alteration status in metastatic biopsy specimen: wild type