Bladder cancer
Management of BCG-pretreated (very) high-risk NMIBCCornelia (72 years old)
Cornelia, a 72-year-old retired naval officer, presented with episodes of macroscopic haematuria.
Assessment summary:
- Medical history:
- Hypertension
- Moderate chronic obstructive pulmonary disease
- ECOG PS: 1
- Cystoscopy:
- 2 papillary tumours: 1 in the trigone, 1 in the right bladder wall
- Largest tumour diameter: 3.5 cm
- Urine cytology: HG UCa (according to the Paris system)
- Conventional TURBT: resection visually complete, pathological review:
- pTa HG
- Pure UCa
- No LVI
- Muscle in specimen
- CT urography: cN0, no concomitant upper tract tumour
BCG induction was started. After the third dose of BCG induction, the patient presents with a strong, persistent urge to urinate, a burning feeling when urinating and microscopic haematuria without fever or other systemic symptoms. The patient was put on non-steroidal anti-inflammatory drugs (NSAIDs), but symptoms did not improve after 1 week.
A urine sample is collected and sent to the lab to be cultured.