Breast cancer
UPDATED --- Adjuvant systemic treatment of luminal A/B early breast cancer in postmenopausal women

Camila (72 years old)

Camila, 72 years old, is a retired dressmaker. Nevertheless, she still makes clothes for her grandchildren. She was diagnosed with early breast cancer after detecting a lump in her right breast on self-examination.

Assessment summary

  • Medical history: osteoporosis with a hip fracture 6 months ago
  • No family history of breast or ovarian cancer
  • Postmenopausal since age 51
  • Stage and tumour biology at diagnosis:
    • cT2N0M0
    • ER 100%, PgR 100%, HER2 IHC 0, Ki67 15%
  • Upfront BCS + SLNB
  • Pathology report:
    • G2 lobular carcinoma
    • Unifocal, 28 mm, pT2
    • LVI or perineural invasion absent
    • R0 resection (free margins)
    • pN0 (0/3 sn)
  • Multidisciplinary board meeting: postoperative RT and endocrine therapy + bisphosphonates

Which of the following systemic treatment options would you choose for this patient?