Bladder cancer
First-line therapy of synchronous and metachronous metastatic UCaDuarte (79 years old)
Duarte, 79 years old, watches a different classic movie every night, turning his living room into a mini cinema. He is diagnosed with metastatic bladder cancer during a workup for haematuria.
Assessment summary:
- Medical history: obese, controlled diabetes mellitus (DM) and diabetic nephropathy, venous leg ulcers
- CT chest, abdomen, pelvis: pelvic lymph node metastases and diffuse liver metastases, liver biopsy compatible with UCa
- ECOG PS: 2
- Peripheral neuropathy: grade 2 due to DM
- No hearing impairment
- GFR: 25 ml/min due to diabetic nephropathy
- Cardiac ejection fraction: 60%
- PD-L1 expression: strongly positive