Breast cancer
UPDATED --- Adjuvant systemic treatment of luminal A/B early breast cancer in premenopausal women

Yelena (43 years old)

Yelena, 43 years old, is a real foody. She regularly visits new restaurants to explore new tastes. She detected a lump in her right breast on self-examination.

Assessment summary

  • Premenopausal
  • No relevant medical history
  • No family history of cancer
  • Stage and tumour biology (core biopsy) at diagnosis:
    • cT2N0M0
    • G2, invasive carcinoma of NST, ER 100%, PgR 10%, HER2 IHC 0, Ki67 20%
  • BCS with oncoplastic techniques + SLNB
  • Pathology report:
    • G2 bifocal invasive carcinoma, 17 mm in largest foci, pT1c(m)
    • LVI or perineural invasion absent
    • R0 resection (free margins)
    • pN0 (0/4 sn)

Which of the following options would you choose for this patient?