Prostate cancer
Management of non-metastatic castration-resistant prostate cancerHans (74 years old)
Hans, 74 years old, mastered playing classical violin and has graced the stage with esteemed orchestras. He was diagnosed with high-risk localised PCa at the age of 66 years, with a PSA of 22 ng/ml and urinary symptoms. He opted for radiotherapy and was treated with EBRT + 3 years of ADT.
6.5 years after diagnosis, the PSA increased to 3.0 ng/ml, prompting imaging with CT and bone scan, which showed no abnormalities. ADT was initiated and PSA decreased to 0.5 ng/ml.
Follow-up information today, 1.5 years after initiation of continuous ADT:
- Medical history: angina pectoris and intermittent atrial fibrillation (ongoing treatment with bisoprolol and apixaban)
- ECOG PS: 1
- PSA: 2.1 ng/ml
- PSA-DT: 8.7 months
- Serum testosterone: 16 ng/dl
- Bone and CT scan: no metastases