Case 3: Harvey (72 years old)

Harvey, 72 years old, has always tried to fix things himself, whether it’s a leaky tap or a creaky floorboard. He was diagnosed with high-grade NMIBC and underwent 6 cycles of BCG. At follow-up cystoscopy, a tumour was found at the bladder neck.

Assessment summary:

• No relevant medical history
• Maximal TURBT, resection visually complete
• Pathological review:
  • Progression to MIBC, at least pT2
  • Pure urothelial carcinoma (UCa)
  • Unifocal, no concomitant CIS
  • Muscle in specimen
• Imaging: suggestive for cT2N0M0
• Ultrasound: no hydronephrosis
• eGFR: 70 ml/min
• No peripheral neuropathy
• No hearing impairment
• ECOG PS: 0
• Cardiac ejection fraction: 60%
• No voiding symptoms