Prostate cancer
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Piet (68 years old)

Piet is a 68-years-old retired railway employee. During a yearly check-up at the GP, his PSA was 4.2 ng/mL. He was referred to a urologist. The initial work-up resulted in the following:

  • DRE: prostate volume (PV) slightly enlarged, no suspicious findings

  • PSA: 4.5 ng/mL

  • PV: 40 mL

Piet is otherwise healthy and has no major comorbidities.

Which of the following options do you consider most appropriate for this patient?