Colin (72 years old)

Colin, 72 years old, was a famous percussionist and had the opportunity to work across several musical genres with a wide range of artists. He was diagnosed with high-risk PCa 5 years ago and treated with RP + ePLND (pT3aN0M0, negative surgical margins, postoperative PSA 0.02 ng/ml).

1 year later, the PSA rose to 0.20 ng/ml. He was treated with salvage EBRT which resulted in an undetectable PSA.

Again 1 year later, the PSA increased to 1.56 ng/ml (N0M0 on bone scan and CT). He received ADT and PSA dropped to 0.08 ng/ml.

The following 3 years, his PSA was monitored. Today, his PSA is 5.3 ng/ml, with a PSA-DT of 6 months (serum testosterone 18 ng/dl).

• Bone scan: negative
• PSMA-PET: 3 positive bone lesions (all vertebral) with a morphologic correlate on CT scan

He is fit (G8 score of 15), has an ECOG PS of 0 and has no relevant comorbidities.