Prostate cancer
Tailoring treatment for metastatic hormone-sensitive prostate cancer

Anthony (51 years old)

Anthony is a 51-year-old baker. He is well-known across the village for his delicious multigrain bread and cherry pies. He was recently diagnosed with metastatic PCa.

  • Medical history: no abnormalities
  • ECOG PS: 0
  • Asymptomatic
  • Bone scan: 1 metastasis (T11)
  • CT: locally advanced prostatic mass, few enlarged lymph nodes within the pelvis, no sign of visceral metastasis
  • PSMA-PET scan: 2 bone metastases and 1 positive lymph node outside the pelvic area
  • PSA: 19 ng/ml
  • Prostate biopsy: ISUP grade 4 (Gleason 4+4)

Which of the following treatment options would you choose for this patient?