Bladder cancer
Adjuvant treatment approaches for MIBC

Barbara (70 years old)

Barbara, 70 years old, was quite a successful fashion stylist. Today she still brags about having met so many celebrities…

She was diagnosed with MIBC (cT3bN0M0) for which she received 4 cycles of neoadjuvant GC and underwent RC + PLND.

Postoperative assessment summary:

  • eGFR: 65 ml/min
  • ECOG PS: 0
  • Pathological review RC specimen:
    • ypT3N0 (0/10)
    • R1
    • PD-L1 positive
  • Imaging: cM0
  • Cardiac ejection fraction: 70%

Which of the following treatment options would you choose for this patient?