Prostate cancer
Tailoring treatment for metastatic hormone-sensitive prostate cancer

Oscar (75 years old)

Oscar is a 75-year-old pigeon fancier. The pigeons like to navigate in the area around his house, and he enjoys their presence, Oscar’s neighbours however, not so much… Oscar was recently diagnosed with metastatic PCa.

  • Medical history: severe COPD
  • ECOG PS: 2
  • Experiences back pain corresponding to the location of the metastatic lesion on bone scan
  • Bone scan: 1 metastasis (T11)
  • CT: locally advanced prostatic mass, few enlarged lymph nodes within the pelvis, no sign of visceral metastasis
  • PSMA-PET scan: 2 bone metastases and 1 positive lymph node outside the pelvic area
  • PSA: 19 ng/ml
  • Prostate biopsy: ISUP grade 4 (Gleason score: 4+4)

Which of the following treatment options would you choose for this patient?