Bladder cancer
UPDATED --- First-line therapy of synchronous and metachronous metastatic UCaJennifer (79 years old)
Jennifer, 79 years old, sings to her plants every morning, convinced that it is necessary for their growth.
She is diagnosed with metastatic bladder cancer during a workup for haematuria.
Assessment summary:
- Medical history: obese, controlled diabetes and diabetic nephropathy, venous leg ulcers
- CT scan of chest, abdomen and pelvis: pelvic lymph node metastases and diffuse liver metastases, liver biopsy compatible with UCa
- ECOG PS: 2
- Peripheral neuropathy: grade 3 due to diabetes
- No hearing impairment
- GFR: 25 ml/min due to diabetic nephropathy
- Cardiac ejection fraction: 60%
- PD-L1 expression: strongly positive