Bladder cancer
First-line therapy of synchronous and metachronous metastatic UCaBruna (79 years old)
Bruna, 79 years old, has always had a big passion for music concerts. To this day she still goes to concerts where she can sit.
She was diagnosed with metastatic bladder cancer during a workup for haematuria.
Assessment summary:
- Medical history: diabetes and diabetic nephropathy
- CT scan of chest, abdomen and pelvis: pelvic lymph node metastases and diffuse liver metastases
- Biopsy compatible with UCa
- ECOG PS: 2
- Peripheral neuropathy: grade 2 due to diabetes
- No hearing impairment
- GFR: 35 ml/min due to diabetic nephropathy
- Cardiac ejection fraction: 70%
- PD-L1 expression: strongly positive