Breast cancer
NEW --- Systemic therapy for early stage TNBC

Katherina (44 years old)

Katherina, 44 years old, is a columnist for a national newspaper. In her free time, she likes to play the violin and attend recitals. She was diagnosed with breast cancer on the left side following screening mammography.

Assessment summary

  • Premenopausal
  • No family history of breast or ovarian cancer
  • No relevant medical history, ECOG PS: 0
  • Tumour size: cT1c (19 mm), LN status: cN1
  • Tumour biology:
    • Ductal invasive carcinoma of NST
    • ER 0%, PgR 0%, HER2 IHC 0
    • Ki67 75%
    • G3
  • CT scan thorax/abdomen and bone scan: no metastases
  • Genetic testing: no BRCA1/2 mutation

Which of the following treatment options would you choose for this patient?