Angela (62 years old)

Angela, 62 years old, is a legal associate at an Embassy in Brussels. She was diagnosed with metastatic breast cancer after she underwent a brain CT for long-term headache associated with nausea.

• No relevant medical history
• Brain CT: multiple suspicious spots
• Neurologic clinical exam: normal
• PET scan: breast lesion, multiple liver lesions and pleural effusion
• Brain MRI: 12 brain lesions (all <1 cm, location: sub- and infratentorial)
• Tumour biology (biopsy breast lesion): ER 0%, PgR 0%, HER2 IHC 3+
• ECOG PS: 0
• Local treatment of brain metastases by WBRT; controlled