Bladder cancer
Histological subtypes of (N)MIBC: managed differently compared to pure UCa?

Austin (33 years old)

Austin is a 33-year-old radio presenter. He is worried about recurrent haematuria and decides to pay his doctor a visit.

Assessment summary:

  • Comorbidities:
    • Spina bifida
    • Indwelling catheter
  • No paralysis
  • Tumour at right bladder wall
  • Maximal TURBT:
    • Minimal pT2 pure squamous cell carcinoma (SCC) 
    • No LVI
    • Unifocal, no concomitant CIS
  • Imaging: suggestive of cT3bN0M0
  • Normal renal function
  • ECOG PS: 1

   

Which treatment option would you choose for this patient?